Papers on Radiobiology and Biomathematics, 1997-98 (Ray Sachs)
RK Sachs, AM Chen and DJ Brenner, Review: proximity effects
in the production of chromosome aberrations by ionizing radiation.
International Journal of Radiation Biology
71, 1-19, 1997.
html Abstract and Introduction
Sachs, RK; Hahnfeldt, P; Brenner, DJ.
Review: The link between low-LET dose-response relations and the
underlying kinetics of damage production/repair/misrepair.
International Journal of Radiation Biology 72, 351-374, 1997.
html Abstract
Rainer K. Sachs, David J. Brenner, Allen M. Chen,
Philip Hahnfeldt, and Lynn R. Hlatky.
Intra-Arm and Inter-Arm Chromosome Intrachanges:
Tools for Probing Chromatin Geometry and Dynamics,
Radiation Research 148, 330-339, 1997.
html Abstract
Sachs, RK; Brenner, DJ.
The mechanistic basis of the LQ formalism.
Medical Physics75, 2071-2073, 1998.
html Paper
Rainer K. Sachs, David J. Brenner, Philip J. Hahnfeldt, and Lynn R. Hlatky.
Modeling Large-Scale Clusters of Radiation-Induced Breaks Along Chromosomes.
International Journal of Radiation Biology, 74,
185-206, 1998.
html Abstract and
Introduction
Hahnfeldt P; Sachs RK. Radiation damage to a dynamic cell
population. In:
Advances in Mathematical Population Dynamics: Molecules, Cells and
Man,
Edited by O.Arino, D.Axelrod, M.Kimmel.
World Scientific Publishing Company, 1998.
Paper in Postscript
Tomas Radivoyevitch, David G. Hoel,
Philip J. Hahnfeldt, Rainer K Sachs,
Size Distributions for Misrejoining DNA Fragments in Irradiated
Cells.
Mathematical Biosciences, 149, 107-136 (1998).
Postscript Abstract
Allen M. Chen, Joe N. Lucas, Paul J. Simpson, Carol S. Griffin,
John R. K. Savage, David J. Brenner, Lynn R. Hlatky and Rainer Sachs.
Computer Simulation of FISH Data on Chromosome Aberrations
Produced by X-rays or alpha Particles
Radiation Research 148, S93-S101, 1997.
html Abstract
H. Wu, R. K. Sachs, T. C. Yang.
Radiation-induced total-deletion mutations in the human hprt gene: a
biophysical model based on random walk interphase chromatin geometry.
International Journal of Radiation Biology
73, 149-156, 1998.
html Abstract
Liu, B; Sachs, RK.
A two-backbone polymer model for interphase chromosome geometry.
Bulletin of Mathematical Biology, 59, 325-337, 1997.
T. Radivoyevitch, D.G. Hoel, P.H. Hahnfeldt, B. Rydberg,
and R.K. Sachs,
Recent Data Obtained by Pulsed-Field Gel Electrophoresis Suggest Two
Types of Double-Strand Breaks.
Radiation Research 149, 52-58, 1998.
html Abstract
T. Radivoyevitch, D.G. Hoel, A.M. Chen and R.K. Sachs,
Misrejoining of double-strand breaks after x-irradiation: relating
moderate to very high doses by a Markov model.
Radiation Research, 149, 59-67, 1998.
html Abstract
H. Wu, M. Durante, R.K. Sachs and T.C. Yang, A random walk model for
interphase chromosomes and the relationship between centric rings,
acentric rings and excess acentric fragments induced by low-LET
radiation.
International Journal of Radiation Biology 71, 487-496, 1997.
A. M. Chen, P. J. Simpson, C. S. Griffin, J. R. K. Savage,
D. J. Brenner, J. N. Lucas, and R. K. Sachs,
Modeling low and high LET FISH data
on simple and complex chromosome aberrations.
In: Microdosimetry: An Interdisciplinary Approach, Edited by: D.T.
Goodhead, P. O'Neill and H.G. Menzel (Royal Society of Chemistry,
Cambridge, UK), pp. 156-159, 1997.
Brenner DJ; Hlatky LR; Hahnfeldt PJ; Huang Y; and Sachs RK.
The linear-quadratic and most other
common radiobiological models predict similar time-dose
relationships.
Radiation Research, 150:83-91, 1998.